Senior Scientist, Vector Construction – Genome Engineering

Boston, MA – cross-functional genetic therapies teams across Vertex to advance our understanding of the science of gene therapy vector manufacture and performance. Minimum Qualifications Ph.D. in cell biology or related field At least 5 years of post-doctoral tissue culture experience, including generation and maintenance of cell lines, transfection, transduction and cell-based assay development 5 years of experience in DNA construction, gene expression cassette design, synthesis, and testing Mammalian Genome… for production of bacterial plasmids Python, Perl, and linux scripting proficiency, in particular as relates to processing of large sequencing data sets Experience in biologics production andor QC Knowledge of next generation sequencing library construction methodologies…

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